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Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2

Hisashi Arase's group (Immunochemistry) and others found that a receptor, LILRA2, recognizes immunoglobulins which are disrupted by microbial pathogens, and inhibits the pathogen growth. The research revealed a novel finding of host defense system for immune evasion, and deepens our understanding about the host defense system against infectious diseases.



Article (External Link)

External Link2

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Contact:

Hisashi Arase
Immunochemistry
Immunology Frontier Research Center (WPI-IFReC), Osaka University

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