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Research
2022.08.05

How myasthenia gravis develops in thymoma patients? (Ohkura & Sakaguchi G, in Nat Commun.)

PRESS RELEASE

Although Myasthenia gravis (MG) frequently develops in thymoma patients, the etiologic factors for MG are not well understood. By constructing a comprehensive atlas of thymoma using bulk and single-cell RNA-sequencing, Naganari Ohkura (IFReC/Graduate School of Medicine, Osaka University, Shimon Sakaguchi (Experimental Immunology, IFReC) identified ectopic expression of neuromuscular molecules in MG-type thymoma.

A new mechanism of regulatory T cell generation

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Contact:
Shimon Sakaguchi

Shimon Sakaguchi (Experimental Immunology)


Tel+81-6-6879-4462
Mailshimonifrec.osaka-u.ac.jp

Immunology Frontier Research Center, Osaka University (WPI-IFReC)