News & Topics
DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine- producing metabolic pathway (Masaru ISHII in Nat Med)
The authors identified the de novo DNA methyltransferase Dnmt3a to be a transcription factor that couples these metabolic changes to osteoclast differentiation.
Nishikawa･Masaru Ishii NAT MED_20150224.pdf
Immunology and Cell Biology
Immunology Frontier Research Center (WPI-IFReC), Osaka University