News & Topics
Research
2018.05.24
Autoimmune Th17 cells induced synovial stromal and innate lymphoid cell secretion of GM-CSF to initiate and augment autoimmune arthritis (Sakaguchi Group, in Immunity)
PRESS RELEASE
Hirota and Sakaguchi's group showed arthritogenic Th17 cells stimulated fibroblast-like synoviocytes via interleukin-17 (IL-17) to secrete the cytokine GM-CSF and also expanded synovial-resident innate lymphoid cells (ILCs) in inflamed joints.
Commentary (PDF)
Article (External Link)
Contact:
Shimon Sakaguchi (Experimental Immunology)
+81-6-6879-4462
shimonifrec.osaka-u.ac.jp