Crohn's disease causes chronic inflammation in the gastrointestinal tract, and its onset is attributed to an excessive immune response of CD4-positive helper T cells.
Mari Murakami (Graduate School of Medicine, Osaka University), Kiyoshi Takeda (Director of IFReC), and the research group identified tissue-resident memory T cells that increase in the intestinal tract of patients with Crohn's disease and exacerbate the condition.

Contact

Kiyoshi Takeda Lab.

ktakedaongene.med.osaka-u.ac.jp

Mucosal Immunology