Abnormalities of the innate immune response have been thought to be a part of the pathology of Behçet's syndrome (BS), which is designated as an incurable disease. However, the detailed mechanism has remained unclear.
A research group of Hyota Takamatsu and Atsushi Kumanogoh (Osaka University Graduate School of Medicine/Immunopathology, IFReC) revealed that the mtDNA wrapped in exosomes is responsible for the inflammatory pathology of BS.

Contact

Prof. Atsushi Kumanogoh

kumanogoimed3.med.osaka-u.ac.jp

Immunopathology