Yoshiaki Yasumizu, Naganari Ohkura (Graduate School of Medicine, Osaka University), and Shimon Sakaguchi (Experimental Immunology, IFReC) and their group compile a comprehensive reference of circulating CD4+ T cells, encompassing 12 gene programs and 18 clusters. They reveal disease-specific cellular characteristics through the integration of genome-wide association studies and single-cell meta-analysis. This work provides insights for precision medicine. 
(online publishing in Cell Genomics on January 4, 2024)

 License: CC-BY 4.0

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Sakaguchi Lab

shimonifrec.osaka-u.ac.jp

Experimental Immunology