Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease characterized by optic neuritis and transverse myelitis, with unclear genetic background. 

A research group led by Yukinori Okada (Graduate School of Medicine, Osaka University/WPI-IFReC/The University of Tokyo/RIKEN) showed a genome-wide meta-analysis of NMOSD in Japanese (240 patients and 50,578 controls) identified significant associations with the major histocompatibility complex region and a common variant close to CCR6.
(Cell Genomics on Feb. 22, 2025)

Contact

Prof. Yukinori Okada

yokadasg.med.osaka-u.ac.jp

Statistical Immunology