News & Topics

Research
2025.04.28

Dissecting cross-population polygenic heterogeneity across respiratory and cardiometabolic diseases (Okada G, in Nat Commun.)

PRESS RELEASE

Multimorbidity is a condition in which a single patient suffers from multiple diseases. Patients with multimorbidity typically experience a poorer quality of life and prognosis compared to those with single diseases, which in turn increases the burden on medical and nursing care systems.

A collaborative research group led by Yukinori Okada (WPI-IFReC/University of Tokyo/RIKEN) investigated the genetic associations between three respiratory and immune diseases, including asthma, and seven cardiometabolic diseases, including rheumatoid arthritis and dyslipidemia. They also examined the characteristics and traits associated with these diseases. Their findings revealed that the relationship between the genetic risk of respiratory and immune diseases and cardiometabolic diseases differs between East Asian and European populations.
(Nature Communications on March 28, 2025)


Contact

Prof. Yukinori Okada

yokadasg.med.osaka-u.ac.jp

Statistical Immunology