Toshihide Yamashita (Molecular Neuroscience, IFReC) and his research group showed the most abundant infiltrating lymphocytes in the developing brain are B cells.

Schematic diagram of the study
B-1a cells in meningeal space secrete natural antibodies,
which promote the proliferation of oligodendrocyte precorsors.
With this mechanism, B-1a cells support the brain development.

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Contact:

Toshihide Yamashita（Molecular Neuroscience）

+81-6-6879-3971
yamashitamolneu.med.osaka-u.ac.jp

Immunology Frontier Research Center, Osaka University (WPI-IFReC)