Natural Killer (NK) cells are immune cells that play a crucial role in the early defense against viral infections and cancer, yet how their diversity is established remains largely unknown.

A research group of Yosuke Kishi (MD Program, Osaka University School of Medicine), Shuhei Sakakibara (Visiting Associate Professor), and Daisuke Okuzaki (Associate Professor, IFReC) analyzed NK cells in the blood of patients with severe COVID-19, as well as in individuals who received an mRNA vaccine, at the single-cell level. Their findings revealed the mechanisms through which NK cells diversify in response to the distinct immune stimuli of COVID-19 infection and vaccination.

Contact

Daisuke Okuzaki Laboratory

dokuzakibiken.osaka-u.ac.jp

Human Immunology（Single Cell Genomics)