Osaka University Immunology Frontier Research Center

Jun. 5, 2013

[IFReC Member Only] Application for Combined & Dual Mentor Program FY2013

Activities

May. 24, 2013

Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation. (Shizuo AKIRA in Cell)

Significant achievements

May. 14, 2013

Arid5a controls IL-6mRNA stability, which contributes to elevation of IL-6 level in vivo. (Tadamitsu KISHIMOTO in PNAS)

Significant achievements

Apr. 19, 2013

The double stranded RNA poly IC triggers a cathepsin D-IPS-1-dependent pathway to enhance cytokine production and mediate dendritic cell necroptosis (Shizuo AKIRA in Immunity)

Significant achievements

Apr. 9, 2013

Hisashi ARASE to be awarded by MEXT

Activities

Apr. 9, 2013

S1P-mediated osteoclast precursor monocyte migration is a critical point of control in anti-bone-resorptive actions of active vitamin D. (Masaru ISHII in PNAS)

Significant achievements

Mar. 21, 2013

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages. (Shizuo AKIRA in Nature)

Significant achievements

Mar. 18, 2013

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome. (Shizuo AKIRA in Nat Immunol)

Significant achievements

Jan. 30, 2013

A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degenerative diseases. (Atsushi KUMANOGOH in Nat Commun)

Significant achievements

Jan. 17, 2013

Dynamic visualization of RANKL and Th17-mediated osteoclast function. (Masaru ISHII in JCI)

Significant achievements