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HOME > News & Topics > Research > FY 2008 > Regulatory T Cells and Immune Tolerance (Review by Prof. Sakaguchi in Cell)

Regulatory T Cells and Immune Tolerance (Review by Prof. Sakaguchi in Cell)

Regulatory T cells (Tregs) play an indispensable role in maintaining immunological unresponsiveness to self-antigens and in suppressing excessive immune responses deleterious to the host.

Recent research reveals the cellular and molecular basis of Treg development and function. The research also implicates the dysregulation of Tregs in immunological disease.


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