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Research FY 2016

BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection (Takeda group, in JEM)
The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help (Kurosaki group, in JEM)
Identification of an atypical monocyte and committed progenitor involved in fibrosis (Akira group, in Nature)
Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin 1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation (Ken Ishii group, in Immunity)
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment (Sakaguchi group, in Nat Immunol)
Diurnal control of adaptive immune responses by adrenergic nerves (Suzuki group, in JEM)
Arid5a exacerbates IFN-γ-mediated septic shock by stabilizing T-bet mRNA (Kishimoto group, in PNAS)
Rabex-5 is a Lenalidomide target molecule that negatively regulates TLR induced type-1 interferon production (Kishimoto group, in PNAS)
Real-time intravital imaging of pH variation associated with osteoclast activity (Kikuchi group and M. Ishii group, in Nat Chem Biol)
Regulated selection of germinal-center cells into the memory B cell compartment (Kurosaki group, in Nat Immunol)
Two FOXP3+CD4+ T-cell subpopulations distinctly control the prognosis of colorectal cancers (Sakaguchi group, in Nat Med)
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system