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Neuron guidance factor Semaphorin 6D plays a key roll in macrophage lipid metabolism and anti-inflammatory polarization (Takamatsu-Kumanogoh Group, in Ann Rheum Dis.)
Neuron guidance factor Semaphorin 6D plays a key roll in macrophage lipid metabolism and anti-inflammatory polarization (Kumanogoh Group, in Nature immunology)
Autoimmune Th17 cells induced synovial stromal and innate lymphoid cell secretion of GM-CSF to initiate and augment autoimmune arthritis (Sakaguchi Group, in Immunity)
T follicular helper cell-germinal center B cell interaction strength regulates entry into plasma cell or recycling GC cell fate (Kurosaki Group, in Immunity)
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.(Okada Group, in Nature Genetics)
B-1a lymphocytes promote oligodendrogenesis during brain development (Yamashita Group, in Nature Neuroscience)
Combination of multiple optical measurements can assess macrophage activation at single-cell level without any contrast agent (Nicholas I. Smith Group, in PNAS)
The subcellular dynamics of Arid5a in response to inflammation.(Kishimoto Group, in PNAS)
Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo.(M.Ishii Group, in Nature Communications)
The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids(Takeda Group, in Immunity)
Discovery of key molecules involved in severe malaria (Arase Group, in Nature)
The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy(Kumanogoh Group, in Nature Medicine)
Peripherally derived FGF21 promotes remyelination in the central nervous system (Yamashita group, in JCI)
Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions (Masaru Ishii group, in Scientific Reports)
A distinct subpopulation of CD25 negative T-follicular regulatory cells localizes in the germinal centers (Sakaguchi group, in PNAS)
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense (Yamamoto group, in Nature Immunology)
Plasmodium products persist in the bone marrow and promote chronic bone loss (Coban group, in Science Immunology)
BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection (Takeda group, in JEM)
The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help (Kurosaki group, in JEM)
Identification of an atypical monocyte and committed progenitor involved in fibrosis (Akira group, in Nature)
Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin 1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation (Ken Ishii group, in Immunity)
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment (Sakaguchi group, in Nat Immunol)
Diurnal control of adaptive immune responses by adrenergic nerves (Suzuki group, in JEM)
Arid5a exacerbates IFN-γ-mediated septic shock by stabilizing T-bet mRNA (Kishimoto group, in PNAS)
Rabex-5 is a Lenalidomide target molecule that negatively regulates TLR induced type-1 interferon production (Kishimoto group, in PNAS)
Real-time intravital imaging of pH variation associated with osteoclast activity (Kikuchi group and M. Ishii group, in Nat Chem Biol)
Regulated selection of germinal-center cells into the memory B cell compartment (Kurosaki group, in Nat Immunol)
Two FOXP3+CD4+ T-cell subpopulations distinctly control the prognosis of colorectal cancers (Sakaguchi group, in Nat Med)
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system