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CXCR4 regulates Plasmodium development in mouse and human hepatocytes (Yamamoto G in JEM)
IL-17-mediated phosphorylation of Regnase-1 (Akira G in JEM)
The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors (Suzuki group in JEM)
Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis (Takakura group in Nat Commun)
Impact of sarcopenia in patients with advanced non-small cell lung cancer treated with PD-1 inhibitors (Kumanogoh group in Sci Rep)
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation (Sakaguchi group in Nat Commun)
Genetic and phenotypic landscape of the MHC region in the Japanese population(Okada group in Nat Gen)
Bacterial metabolites lactate and pyruvate have big effects on the intestinal immune response.(Takeda group, in Nature)
TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity (Takakura group, in Dev. Cell)
Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells (Kumanogoh group, in NAR)
Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity (Okada group, in NAR)
Lipoteichoic acid anchor triggers Mincle to drive protective immunityagainst invasive group A Streptococcus infection (Yamasaki group, in PNAS)
Inducible Nitric Oxide synthase is a key host factor for Toxoplasma GRA15-dependent disruption of the γ interferon-induced antiparasitic human response (Yamamoto group, in mBio)
Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients (Shohei Koyama (Kumanogoh Group) in JCI insight)
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors (Shohei Koyama (Kumanogoh Group) in Nature Medicine)
Heme ameliorates the colitis through providing intestinal macrophages with non-inflammatory profiles (Takeda group, in PNAS)
Neuron guidance factor Semaphorin 6D plays a key roll in macrophage lipid metabolism and anti-inflammatory polarization (Takamatsu-Kumanogoh Group, in Ann Rheum Dis.)
Neuron guidance factor Semaphorin 6D plays a key roll in macrophage lipid metabolism and anti-inflammatory polarization (Kumanogoh Group, in Nature immunology)
Autoimmune Th17 cells induced synovial stromal and innate lymphoid cell secretion of GM-CSF to initiate and augment autoimmune arthritis (Sakaguchi Group, in Immunity)
T follicular helper cell-germinal center B cell interaction strength regulates entry into plasma cell or recycling GC cell fate (Kurosaki Group, in Immunity)
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.(Okada Group, in Nature Genetics)
B-1a lymphocytes promote oligodendrogenesis during brain development (Yamashita Group, in Nature Neuroscience)
Combination of multiple optical measurements can assess macrophage activation at single-cell level without any contrast agent (Nicholas I. Smith Group, in PNAS)
The subcellular dynamics of Arid5a in response to inflammation.(Kishimoto Group, in PNAS)
Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo.(M.Ishii Group, in Nature Communications)
The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids(Takeda Group, in Immunity)
Discovery of key molecules involved in severe malaria (Arase Group, in Nature)
The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy(Kumanogoh Group, in Nature Medicine)
Peripherally derived FGF21 promotes remyelination in the central nervous system (Yamashita group, in JCI)
Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions (Masaru Ishii group, in Scientific Reports)