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Research FY 2017

The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy(Kumanogoh Group, in Nature Medicine)
 
Peripherally derived FGF21 promotes remyelination in the central nervous system (Yamashita group, in JCI)
 
Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions (Masaru Ishii group, in Scientific Reports)
 
A distinct subpopulation of CD25 negative T-follicular regulatory cells localizes in the germinal centers (Sakaguchi group, in PNAS)
 
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense (Yamamoto group, in Nature Immunology)
 
Plasmodium products persist in the bone marrow and promote chronic bone loss (Coban group, in Science Immunology)
 

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