News & Topics
Research
2014.12.19
Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4 (Shimon SAKAGUCHI in Immunity)
PRESS RELEASE
The authors found Treg cells directly inhibited, via CTLA-4, B cell expression of CD80 and CD86, which was essential for Tfh cell formation.
Wing･Sakaguchi IMMUNITY_20141219.pdf
Article
Contact:
Shimon SAKAGUCHIExperimental Immunology
Immunology Frontier Research Center (WPI-IFReC), Osaka University