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HOME > News & Topics > Research > FY 2018 > Lipoteichoic acid anchor triggers Mincle to drive protective immunityagainst invasive group A Streptococcus infection (Yamasaki group, in PNAS)

Lipoteichoic acid anchor triggers Mincle to drive protective immunityagainst invasive group A Streptococcus infection (Yamasaki group, in PNAS)

Sho Yamasaki and his research group showed that the innate immune receptor Mincle (macrophage inducible Ctype lectin) plays pivotal roles against invasive GAS (group A Streptococcus) infection.

Figure  n this study, the authors showed that the innate immune receptor Mincle (macrophage inducible Ctype lectin)
plays pivotal roles against invasive GAS infection through the recognition of monoglucosyldiacylglycerol (MGDG),
a component of the lipoteichoic acid anchor.



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Contact:
Molecular Immunology Sho Yamasaki

Sho Yamasaki(Molecular Immunology)


Tel+81-6-6879-8306
Mailyamasakibiken.osaka-u.ac.jp

Immunology Frontier Research Center, Osaka University (WPI-IFReC)

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