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Research
2018.10.23

Lipoteichoic acid anchor triggers Mincle to drive protective immunityagainst invasive group A Streptococcus infection (Yamasaki group, in PNAS)

PRESS RELEASE

Sho Yamasaki and his research group showed that the innate immune receptor Mincle (macrophage inducible Ctype lectin) plays pivotal roles against invasive GAS (group A Streptococcus) infection.

Figure  n this study, the authors showed that the innate immune receptor Mincle (macrophage inducible Ctype lectin)
plays pivotal roles against invasive GAS infection through the recognition of monoglucosyldiacylglycerol (MGDG),
a component of the lipoteichoic acid anchor.



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Contact:
Molecular Immunology Sho Yamasaki

Sho Yamasaki(Molecular Immunology)


Tel+81-6-6879-8306
Mailyamasakibiken.osaka-u.ac.jp

Immunology Frontier Research Center, Osaka University (WPI-IFReC)