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"How bone marrow regenerates after chemotherapy?" (Masaru Ishii G, in JEM)

The research group of Prof. Masaru Ishii (Immunology and Cell Biology, IFReC/Graduate School of Medicine, Osaka University) identified the molecular mechanism by which HSPCs (hematopoietic stem and progenitor cells) recover after injury.

figure Figure 1. Schematic of a novel mechanism of hematopoietic recovery. After chemotherapy, bone marrow-resident group 2 innate lymphoid cells (ILC2s) receive cytokine signals from dying cells and support hematopoietic recovery through secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF). (credit: Osaka University)


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Contact:
Masaru Ishii

Masaru Ishii Lab.

Tel06-6879-3881
Mail mishiiicb.med.osaka-u.ac.jp

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