By designing an immune antigen targeting the core region of the spike protein RBD (Receptor Binding Domain), which is structurally conserved among SARS-related viruses, the research group of Ryo Shinnakasu, Tomohiro Kurosaki (Lymphocyte Differentiation, IFReC), and Shuhei Sakakibara (Immune Regulation, IFReC) succeeded in efficiently inducing neutralizing antibodies with broad efficacy.

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