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CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis (Kinoshita G, in PNAS)

The research group of Taroh Kinoshita (Immunoglycobiology, IFReC/RIMD Osaka University) reported a genome-wide CRISPR knockout screen of genes required for rescuing GPI-anchored protein expression after addition of chemically synthesized GlcNAc-PI to PIGA-knockout cells that cannot synthesize GlcNAc-PI.


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Commentary(PDF)

Article (external link)

Contact:
Taroh Kinoshita

Taroh Kinoshita (Immunoglycobiology)


WPI Immunology Frontier Research Center

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