News & Topics
Aldh1a2+ fibroblastic reticular cells regulate lymphocyte recruitment in omental milky spots. (Okabe G, in JEM)
Lymphoid clusters in visceral adipose tissue omentum, known as milky spots, play a central role in the immunological defense in the abdomen. However, their development and maturation mechanisms are poorly understood.
Tomomi Yoshihara and Yasutaka Okabe (Lab. Immune Homeostasis, IFReC) identified a subset of fibroblastic reticular cells (FRCs) that are uniquely present in omental milky spots.
Yasutaka Okabe Lab.