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HOME > News & Topics > Research > FY 2015 > CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability(Tomohiro Kurosaki in JEM)

CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability(Tomohiro Kurosaki in JEM)

Inoue and Kurosaki group (Lymphocyte Differentiation, IFReC) showed mice lacking the CNOT3 subunit of CCR4-NOT deadenylase complex, specifically in B cells, have a developmental block at the pro- to pre-B cell transition.

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Tomohiro Kurosaki

Tomohiro Kurosaki(Lymphocyte Differentiation)

Tel +81-6-6879-4456 Mail kurosakiatmarkifrec.osaka-u.ac.jp

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