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Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system

An IFReC interdisciplinary project was conducted by a group including Alexis Vandenbon (Immuno-Genomics Unit) and Shimon Sakaguchi (Experimental Immunology) that developed Immuno-Navigator--a database for correlation of expression in cells of the immune system. They used Immuno-Navigator to predict key regulators in naturally occurring regulatory T cells, and the role of a candidate regulator was further confirmed through an experiment. Immuno-Navigator is expected to enhance the analysis and understanding of big data stemming from immunology research.

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Immuno-Navigator

Contact:

Shimon Sakaguchi
Experimental Immunology
Immunology Frontier Research Center (WPI-IFReC), Osaka University

Alexis Vandenbon
Immuno Genomics
Immunology Frontier Research Center (WPI-IFReC), Osaka University

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