News & Topics

HOME > News & Topics > Research > FY 2020 > IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome (Kishimoto G, in PNAS)

IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome (Kishimoto G, in PNAS)

Cytokine release syndrome (CRS) is a life-threatening complication induced by hyperinflammatory responses.
Sujin Kang, Tadamitsu Kishimoto (Immune Regulation, IFReC) and the research group found that interleukin (IL)-6 signaling plays a crucial role in endothelial cell dysfunction during bacterial and viral CRS.

figure

Commentary (PDF)


Article (External Link)


Contact:
Tadamitsu Kishimoto

Tadamitsu Kishimoto(Immune Regulation)


Tel+81-6-6879-4956
Mail kishimotoifrec.osaka-u.ac.jp

Immunology Frontier Research Center, Osaka University (WPI-IFReC)

Archives

 
TOPに戻る